ATF3 抗体 (AA 140-168)
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Quick Overview for ATF3 抗体 (AA 140-168) (ABIN3029847)
抗原
See all ATF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-168
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Bovine
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 140-168 from the human protein was used as the immunogen for this ATF3 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ATF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ATF3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ATF3 (Activating Transcription Factor 3 (ATF3))
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别名
- ATF3
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背景
- Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
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UniProt
- P18847
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途径
- Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
抗原
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