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ARF1 抗体 (AA 80-106)

This anti-ARF1 antibody is a 兔 多克隆 antibody detecting ARF1 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN3029877
发货至: 中国

Quick Overview for ARF1 抗体 (AA 80-106) (ABIN3029877)

抗原

See all ARF1 抗体
ARF1 (ADP-Ribosylation Factor 1 (ARF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ARF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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    AA 80-106

    交叉反应 (详细)

    Expected species reactivity: Mouse, Rat, Bovine, Primate, Xenopus

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 80-106 from the human protein was used as the immunogen for this ARF1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the ARF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the ARF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ARF1 (ADP-Ribosylation Factor 1 (ARF1))

    别名

    ARF1

    背景

    ARF1 is a GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD). [UniProt]

    UniProt

    P84077

    途径

    Transition Metal Ion Homeostasis, Inositol Metabolic Process
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