Androgen Receptor 抗体 (AA 282-309)
Quick Overview for Androgen Receptor 抗体 (AA 282-309) (ABIN3029942)
抗原
See all Androgen Receptor (AR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 282-309
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交叉反应 （详细）
- Expected species reactivity: Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 282-309 from the human protein was used as the immunogen for this AR antibody.
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亚型
- Ig Fraction
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anti-Androgen Receptor (AR) antibody
AR 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (N-Term) antibodyAR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) antibodyAR 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Androgen Receptor (AR) antibodyAR 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 491-679) antibodyAR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Androgen Receptor (AR) (N-Term) antibodyVerified AR 适用: 人 WB, IHC, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 221-320) antibodyAR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Androgen Receptor (AR) (AA 15-246) antibodyAR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 365-392) antibodyAR 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 825-919) antibodyAR 适用: 人, 小鼠, 大鼠, Pig, 山羊 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the AR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the AR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Androgen Receptor (AR)
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别名
- AR
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背景
- The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq].
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UniProt
- P10275
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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