NLRP12 抗体
Our Local Distributor
北京 101111
Quick Overview for NLRP12 抗体 (ABIN3032016)
抗原
See all NLRP12 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Antigen affinity purified
-
免疫原
- This anti-NLRP12 antibody was produced from rabbits immunized with human NLRP12 recombinant protein.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the anti-NLRP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the anti-NLRP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
-
别名
- NLRP12
-
背景
- NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes.
-
UniProt
- P59046
-
途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
-