Titration of the AMPK alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:500
限制
仅限研究用
状态
Liquid
缓冲液
In 1X PBS pH 7.4 with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the AMPK alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原
AMPK alpha (SNF1A)
(SNF1A/AMP-Activated Protein Kinase (SNF1A))
别名
AMPK alpha
背景
AMPK alpha is the catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. [UniProt]