ALK 抗体 (AA 636-666)
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北京 101111
Quick Overview for ALK 抗体 (AA 636-666) (ABIN3029939)
抗原
See all ALK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 636-666
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纯化方法
- Purified
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免疫原
- A portion of amino acids 636-666 from the human protein was used as the immunogen for this ALK antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the ALK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ALK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))
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别名
- ALK
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背景
- Anaplastic lymphoma kinase, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2,5)(p23,q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
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UniProt
- Q9UM73
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途径
- RTK signaling
抗原
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