ACE2 抗体 (AA 59-90)
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北京 101111
Quick Overview for ACE2 抗体 (AA 59-90) (ABIN3029962)
抗原
See all ACE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-90
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纯化方法
- Purified
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免疫原
- A portion of amino acids 59-90 from the human protein was used as the immunogen for this ACE2 antibody.
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亚型
- Ig Fraction
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anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 601-700) antibody
ACE2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-250) antibodyACE2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) antibodyACE2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal AC18F unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 93-464) antibodyACE2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 392-739) antibodyACE2 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (N-Term) antibodyVerified ACE2 适用: 人 WB, IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 773-805), (C-Term) antibodyACE2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4819 unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 140-172) antibodyACE2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 351-450) antibodyACE2 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 395-638) antibodyACE2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ACE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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别名
- ACE2
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背景
- This gene encodes a deduced 805-amino acid protein containing a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It also possesses a zinc metalloprotease consensus sequence and a conserved glutamine residue that may function as a third zinc ligand. ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator. Spike (S) proteins of coronaviruses, including the SARS coronavirus, bind with cellular receptors to mediate infection of target cells. ACE-2 binds the S1 domain of the SARS coronavirus S protein. SARS coronavirus replicates efficiently on ACE2-transfected but not mock-transfected 293T cells. Anti-ACE-2 but not anti-ACE1 antibody blocks viral replication on Vero E6 cells. It has been proposed that ACE2 is a functional receptor for SARS coronavirus.
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UniProt
- Q9BYF1
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
抗原
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