PKM2 抗体
Quick Overview for PKM2 抗体 (ABIN4953284)
抗原
See all PKM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity
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免疫原
- A human recombinant partial protein was used as the immunogen for this PKM2 antibody.
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亚型
- IgG1
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anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 适用: 人 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibodyPKM2 适用: 人 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibodyPKM2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p), IF 宿主: 兔 Polyclonal RB3697 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibodyPKM2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18405 unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibodyPKM2 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibodyPKM2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibodyPKM2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase M2 (PKM2) (AA 51-150) antibodyPKM2 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the PKM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,ICC/IF: 1:400
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限制
- 仅限研究用
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缓冲液
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
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储存条件
- -20 °C
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储存方法
- Store the PKM2 antibody at -20°C.
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- PKM2 (Pyruvate Kinase M2 (PKM2))
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别名
- Pyruvate Kinase / PKM2
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背景
- Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. [UniProt]
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UniProt
- P14618
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途径
- Warburg Effect
抗原
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