NLRP12 抗体
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北京 101111
Quick Overview for NLRP12 抗体 (ABIN3032018)
抗原
See all NLRP12 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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免疫原
- This NALP12 antibody was produced from a mouse immunized with NLRP12/NALP12 recombinant protein.
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亚型
- IgM kappa
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应用备注
- The stated application concentrations are suggested starting points. Titration of the NALP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1:1500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4°C for up to one month. For long term, aliquot the NALP12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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别名
- NALP12 (NLRP12)
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背景
- This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
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UniProt
- P59046
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途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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