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HTRA2 抗体

The 小鼠 单克隆 anti-HTRA2 antibody (Clone 8G11-4B8-4F10-G5) (ABIN4953263) specifically detects HTRA2 in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN4953263
发货至: 中国
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Quick Overview for HTRA2 抗体 (ABIN4953263)

抗原

See all HTRA2 抗体
HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

适用

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宿主

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小鼠

克隆类型

  • 81
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单克隆

标记

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This HTRA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

8G11-4B8-4F10-G5
  • 纯化方法

    Protein G affinity

    免疫原

    A human recombinant protein was used as the immunogen for this HtrA2 antibody.

    亚型

    IgG1
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the HtrA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunoprecipitation: suitable

    限制

    仅限研究用
  • 缓冲液

    Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

    储存条件

    -20 °C

    储存方法

    Store the HtrA2 antibody at -20°C.
  • 抗原

    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

    别名

    HtrA2 / Omi

    背景

    Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. [UniProt]

    UniProt

    O43464

    途径

    Positive Regulation of Endopeptidase Activity
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