HTRA2 抗体
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北京 101111
Quick Overview for HTRA2 抗体 (ABIN4953263)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity
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免疫原
- A human recombinant protein was used as the immunogen for this HtrA2 antibody.
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亚型
- IgG1
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应用备注
- The stated application concentrations are suggested starting points. Titration of the HtrA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunoprecipitation: suitable
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限制
- 仅限研究用
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缓冲液
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
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储存条件
- -20 °C
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储存方法
- Store the HtrA2 antibody at -20°C.
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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别名
- HtrA2 / Omi
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背景
- Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. [UniProt]
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UniProt
- O43464
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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