HDAC6 抗体
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北京 101111
Quick Overview for HDAC6 抗体 (ABIN4953258)
抗原
See all HDAC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity
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免疫原
- A human recombinant protein was used as the immunogen for this HDAC6 antibody.
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亚型
- IgG2a
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应用备注
- The stated application concentrations are suggested starting points. Titration of the HDAC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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缓冲液
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
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储存条件
- -20 °C
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储存方法
- Store the HDAC6 antibody at -20°C.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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别名
- HDAC6
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背景
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. [UniProt]
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UniProt
- Q9UBN7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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