The stated application concentrations are suggested starting points. Titration of the HDAC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
缓冲液
Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
储存条件
-20 °C
储存方法
Store the HDAC6 antibody at -20°C.
抗原
HDAC6
(Histone Deacetylase 6 (HDAC6))
别名
HDAC6
背景
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. [UniProt]