SMAD6 抗体 (AA 358-386)
Quick Overview for SMAD6 抗体 (AA 358-386) (ABIN3032629)
抗原
See all SMAD6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 358-386
-
交叉反应 （详细）
- Expected species reactivity: Mouse
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 358-386 from the human protein was used as the immunogen for this SMAD6 antibody.
-
亚型
- Ig Fraction
-
-
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibody
SMAD6 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-384) antibodySMAD6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A6 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 261-495) antibodySMAD6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-385) antibodySMAD6 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 1-496) antibodySMAD6 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 137-182) antibodySMAD6 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (N-Term) antibodySMAD6 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 357-386), (C-Term) antibodySMAD6 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41931 unconjugated
anti-SMAD, Mothers Against DPP Homolog 6 (SMAD6) (AA 285-385) antibodySMAD6 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4C8 unconjugated
-
-
应用备注
- The stated application concentrations are suggested starting amounts. Titration of the SMAD6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at 4°C for up to one month. For long term, aliquot the SMAD6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
-
别名
- SMAD6
-
背景
- SMAD6 acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [UniProt]
-
UniProt
- O43541
-
途径
- Chromatin Binding
抗原
-
