TLR7 抗体
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北京 101111
Quick Overview for TLR7 抗体 (ABIN4952861)
抗原
See all TLR7 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity
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免疫原
- Amino acids QAHPYFWQCLKNALATDNHVAYSQVFKE of human TLR7 were used as the immunogen for the TLR7 antibody.
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亚型
- IgG
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anti-Toll-Like Receptor 7 (TLR7) (AA 30-230) antibody
TLR7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 461-560) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 465-483) antibodyTLR7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 900-950) antibodyTLR7 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 27-126) antibodyTLR7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 706-728) antibody (FITC)TLR7 适用: 人, 小鼠 FACS 宿主: 兔 Polyclonal FITC
anti-Toll-Like Receptor 7 (TLR7) (AA 890-1037) antibodyTLR7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 451-500) antibodyTLR7 适用: 人 ELISA, ICC, FACS, IF 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 706-728) antibodyTLR7 适用: 人, 小鼠 WB, IHC, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the TLR7 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,Immunocytochemistry: 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the TLR7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- TLR7 (Toll-Like Receptor 7 (TLR7))
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别名
- TLR7
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背景
- TLR7 (Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.
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UniProt
- Q9NYK1
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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