BCAR3 抗体
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北京 101111
Quick Overview for BCAR3 抗体 (ABIN4950307)
抗原
See all BCAR3 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity
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免疫原
- Amino acids KGAQVNQTERYEKFNQILTALSRKLEPPPVKQAEL of human BCAR3 were used as the immunogen for the BCAR3 antibody.
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亚型
- IgG
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anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (C-Term) antibody
BCAR3 适用: 人, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (C-Term) antibodyBCAR3 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (AA 266-373) antibodyBCAR3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (C-Term) antibodyBCAR3 适用: 人, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (AA 785-818), (C-Term) antibodyBCAR3 适用: 小鼠 WB 宿主: 兔 Polyclonal RB43280 unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (C-Term) antibodyVerified BCAR3 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (AA 548-818) antibodyBCAR3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Anti-Estrogen Resistance 3 (BCAR3) (AA 761-810) antibodyBCAR3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the BCAR3 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the BCAR3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
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别名
- BCAR3
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背景
- Breast cancer anti-estrogen resistance protein 3 is a protein that in humans is encoded by the BCAR3 gene. Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. BCAR3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- O75815
抗原
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