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BAG2 抗体 (AA 1-211)

This anti-BAG2 antibody is a 兔 多克隆 antibody detecting BAG2 in WB 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN4950288
发货至: 中国

Quick Overview for BAG2 抗体 (AA 1-211) (ABIN4950288)

抗原

See all BAG2 抗体
BAG2 (BCL2-Associated Athanogene 2 (BAG2))

适用

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人, 大鼠, 小鼠

宿主

  • 54
  • 7
  • 1

克隆类型

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  • 8
多克隆

标记

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This BAG2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 10
    • 8
    • 7
    • 2
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    • 1
    • 1
    • 1
    • 1
    AA 1-211

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 1-211 of human BAG2 were used as the immunogen for the BAG2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the BAG2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the BAG2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    BAG2 (BCL2-Associated Athanogene 2 (BAG2))

    别名

    BAG2

    背景

    BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.

    UniProt

    O95816
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