Transferrin Receptor 抗体 (Extracellular)
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Quick Overview for Transferrin Receptor 抗体 (Extracellular) (ABIN4949928)
抗原
See all Transferrin Receptor (TFRC) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 94-212, Extracellular
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原理
- CD71 Antibody / Transferrin Receptor (Extracellular domain) (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 94-212 (extracellular domain) of the human protein were used as the immunogen for the Transferrin Receptor / CD71 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the CD71 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CD71 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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别名
- CD71
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背景
- It recognizes a ~85-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
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UniProt
- P02786
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途径
- Transition Metal Ion Homeostasis
抗原
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