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TIMP2 抗体 (N-Term)

The 小鼠 单克隆 anti-TIMP2 antibody (Clone SPM356) (ABIN4949918) specifically detects TIMP2 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN4949918
发货至: 中国
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Quick Overview for TIMP2 抗体 (N-Term) (ABIN4949918)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TIMP2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

SPM356
  • 抗原表位

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    N-Term

    原理

    TIMP2 Antibody (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP2 antibody to be titered up or down for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    背景

    It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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