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TIMP2 抗体 (N-Term)

This anti-TIMP2 antibody is a 小鼠 单克隆 antibody detecting TIMP2 in WB, IF 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN4949918
发货至: 中国

Quick Overview for TIMP2 抗体 (N-Term) (ABIN4949918)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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人, 大鼠, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This TIMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SPM356
  • 抗原表位

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    N-Term

    纯化方法

    Protein G affinity chromatography

    免疫原

    An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

    亚型

    IgG2a kappa
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP2 antibody to be titered up or down for optimal performance.\. IHC (FFPE): 0.5-1 μg/mL for 30 min at RT,WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the TIMP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    背景

    It recognizes a protein of 21  kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72  kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92  kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

    途径

    cAMP Metabolic Process
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