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TIMP2 抗体 (AA 56-66)

This 小鼠 单克隆 antibody specifically detects TIMP2 in WB, IF, IHC (p) 和 FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN4949916
发货至: 中国
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Room 801-803
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Quick Overview for TIMP2 抗体 (AA 56-66) (ABIN4949916)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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人, 大鼠, 小鼠

宿主

  • 156
  • 65
  • 8
  • 3
  • 1
小鼠

克隆类型

  • 127
  • 106
单克隆

标记

  • 99
  • 22
  • 9
  • 5
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This TIMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

3A4
  • 抗原表位

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    • 15
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    • 3
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    AA 56-66

    原理

    TIMP-2 Antibody (azide and preservative free)

    序列

    DSGNDIYGNP I

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP-2 antibody to be titered up or down for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the TIMP-2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP-2

    背景

    It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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