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TIMP2 抗体 (AA 56-66)

This anti-TIMP2 antibody is a 小鼠 单克隆 antibody detecting TIMP2 in WB, IF 和 IHC (p). Suitable for 人, 大鼠, 小鼠, Cow, 斑马鱼, 兔 和 豚鼠.
产品编号 ABIN4949915
发货至: 中国

Quick Overview for TIMP2 抗体 (AA 56-66) (ABIN4949915)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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人, 大鼠, 小鼠, Cow, 斑马鱼, 兔, 豚鼠

宿主

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小鼠

克隆类型

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  • 83
单克隆

标记

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This TIMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

3A4
  • 抗原表位

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    AA 56-66

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.

    亚型

    IgG2a kappa
  • 应用备注

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP-2 antibody to be titered up or down for optimal performance.\. IHC (FFPE): 0.5-1 μg/mL for 30 min at RT,WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the TIMP-2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    背景

    It recognizes a protein of 21  kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72  kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92  kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

    途径

    cAMP Metabolic Process
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