Optimal dilution of the Podoplanin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 0.5-1 μg/mL,FACS: 0.5-1 μg/million cells in 0.1ml,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
限制
仅限研究用
浓度
1 mg/mL
缓冲液
1 mg/mL in 1X PBS, BSA free, sodium azide free
储存液
Azide free
储存条件
4 °C,-20 °C
储存方法
Store the Podoplanin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
抗原
Podoplanin (PDPN)
别名
Podoplanin / gp36
背景
Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.