Podoplanin 抗体 (AA 24-126)
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Quick Overview for Podoplanin 抗体 (AA 24-126) (ABIN4949854)
抗原
See all Podoplanin (PDPN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 24-126
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纯化方法
- Protein G affinity chromatography
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免疫原
- A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.
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亚型
- IgG1 kappa
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应用备注
- Optimal dilution of the Podoplanin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 0.5-1 μg/mL,FACS: 0.5-1 μg/million cells in 0.1ml,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Podoplanin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Podoplanin (PDPN)
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别名
- Podoplanin / gp36
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背景
- Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
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途径
- Dicarboxylic Acid Transport
抗原
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