MMP2 抗体 (AA 195-319)
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Quick Overview for MMP2 抗体 (AA 195-319) (ABIN4949794)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 195-319
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 195-319 were used as the immunogen for the MMP2 antibody.
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亚型
- IgG1
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the MMP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 0.5-1 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the MMP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP2
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背景
- It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP2 secretion requires the Ras signaling pathway.
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途径
- Activation of Innate immune Response
抗原
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