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CD81 抗体

This anti-CD81 antibody is a 小鼠 单克隆 antibody detecting CD81 in FACS, WB, IF, Func 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4949542
发货至: 中国

Quick Overview for CD81 抗体 (ABIN4949542)

抗原

See all CD81 抗体
CD81

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD81 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1-3-3-22
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal dilution of the CD81 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,Functional Studies: order BSA free formulation,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the CD81 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    CD81

    别名

    CD81

    背景

    This mAb recognizes a protein of 26  kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

    途径

    Inositol Metabolic Process, Hepatitis C
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