Titering of the BAFF antibody may be required for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL
限制
仅限研究用
浓度
1 mg/mL
缓冲液
1 mg/mL in sterile PBS, BSA free, sodium azide free
储存液
Azide free
储存条件
4 °C,-20 °C
储存方法
BAFF antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
抗原
BAFF (TNFSF13B)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
别名
BAFF / BLyS
背景
BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).