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Recombinant PD-1 抗体

This anti-PD-1 antibody is a 兔 单克隆 antibody detecting PD-1 in FACS, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN4949389
发货至: 中国

Quick Overview for Recombinant PD-1 抗体 (ABIN4949389)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

抗体类型

Recombinant Antibody

适用

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克隆类型

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单克隆

标记

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This PD-1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PDCD1-1410R
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    A partial length human protein was used as the immunogen for the recombinant PD1 antibody.

    亚型

    IgG kappa
  • 应用备注

    Titering of the recombinant PD1 antibody may be required for optimal performance.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1),Immunofluorescence: 1-2 μg/mL,FACS: 0.5-1 μg/10e6 cells in 0.1ml

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    PDCD1 / PD-1

    背景

    PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

    途径

    Cancer Immune Checkpoints
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