PD-1 抗体
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北京 101111
Quick Overview for PD-1 抗体 (ABIN4949386)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Protein A affinity chromatography
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免疫原
- A full-length human protein was used as the immunogen for the PD1 antibody.
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亚型
- IgG
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应用备注
- Titering of the PD1 antibody may be required for optimal performance.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Immunofluorescence: 1-2 μg/mL,FACS: 0.5-1 μg/10e6 cells in 0.1ml
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
- PDCD1 / PD-1
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背景
- PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
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途径
- Cancer Immune Checkpoints
抗原
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