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CD20 (B Cells) 抗体

This anti-CD20 (B Cells) antibody is a 兔 多克隆 antibody detecting CD20 (B Cells) in FACS, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN4949281
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD20 (B Cells) 抗体 (ABIN4949281)

抗原

CD20 (B Cells)

适用

宿主

  • 2
  • 1

克隆类型

  • 2
  • 1
多克隆

标记

  • 3
非结合性

应用范围

  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    Recombinant human CD20 protein was used as the immunogen for this CD20 antibody.

    亚型

    IgG
  • 应用备注

    Titering of the CD20 antibody may be required for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    CD20 antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD20 (B Cells)

    别名

    CD20 (B-cell marker)

    背景

    CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.
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