CD4 抗体 (N-Term)
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北京 101111
Quick Overview for CD4 抗体 (N-Term) (ABIN492544)
抗原
See all CD4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- Recognizes CD4
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产品特性
- Synonyms: T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- A 193 amino acid recombinant protein from near the amino terminus of Human CD4(GenBank accession No. NP_000607)
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亚型
- IgG
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应用备注
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ELISA. Western Blot: CD4 antibody can be used for detection of CD4 at 0.5-1 μg/mL. Positive Control: Rat Lung Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CD4
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别名
- CD4
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背景
- CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 Molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
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基因ID
- 920
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UniProt
- P01730
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途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
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