BIM 抗体 (AA 2-198)
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北京 101111
Quick Overview for BIM 抗体 (AA 2-198) (ABIN492532)
抗原
See all BIM (BCL2L11) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2-198
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特异性
- Recognizes Bcl-2-like 11/Bim (2-198).
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产品特性
- Synonyms: Bcl2-L-11, BCL2L11, BIM, BimEL, BimL, BimS, Bcl2-interacting mediator of cell death
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纯化方法
- Immunoaffinity Chromotography.
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免疫原
- A recombinant protein corresponding to amino acids 2 to 198 of Human Bim (NP_619527).
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亚型
- IgG
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应用备注
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ELISA. Western Blot: Bim antibody can be used for detection of Bim at 0.5-1 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch. -
有效期
- 12 months
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- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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背景
- Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.Synonyms: BCL2L11, BIM, Bcl2-L-11, Bcl2-interacting mediator of cell death, BimEL, BimL, BimS
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基因ID
- 10018
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UniProt
- O43521
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途径
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
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