LY9 抗体
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北京 101111
Quick Overview for LY9 抗体 (ABIN492431)
抗原
See all LY9 (CD229) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody recognizes CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
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交叉反应 (详细)
- Species reactivity (tested):Human
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产品特性
- Synonyms: Ly-9, T-lymphocyte surface antigen Ly-9, Lymphocyte antigen 9
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纯化方法
- Protein A affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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免疫原
- CD299-transfected 300. 19 pre-B cell line
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亚型
- IgG1
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应用备注
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Flow cytometry: Use peripheral blood lymphocytes as positive control. Immunoprecipitation. Western blot. Immunocytochemistry. Functional Application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
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别名
- CD229 / LY9
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背景
- CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.Synonyms: Ly-9, Lymphocyte antigen 9, T-lymphocyte surface antigen Ly-9
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基因ID
- 4063
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UniProt
- Q9HBG7
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途径
- BCR Signaling
抗原
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