ULK3 抗体
Quick Overview for ULK3 抗体 (ABIN4915037)
抗原
See all ULK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3.
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亚型
- IgG1
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anti-Unc-51-Like Kinase 3 (ULK3) (AA 435-468), (C-Term) antibody
ULK3 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 1404CT148-89-25 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (Internal Region) antibodyULK3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 427-454), (C-Term) antibodyULK3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 14-43), (N-Term) antibodyULK3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12633 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 44-240) antibodyULK3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 1-214) antibodyULK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 445-458) antibodyVerified ULK3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (C-Term) antibodyVerified ULK3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 324-373) antibodyULK3 适用: 人, 小鼠, 大鼠, 犬, Pig, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ULK3 (Unc-51-Like Kinase 3 (ULK3))
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别名
- ULK3
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背景
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Synonyms: Serine/threonine-protein kinase ULK3, Unc-51-like kinase 3, ULK3
Background: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
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基因ID
- 25989
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UniProt
- Q6PHR2
抗原
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