SLC26A6 抗体 (AA 431-500) (Cy5.5)
Quick Overview for SLC26A6 抗体 (AA 431-500) (Cy5.5) (ABIN4914090)
抗原
See all SLC26A6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 431-500
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交叉反应
- Pig, 大鼠
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预测反应
- Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SLC26A6
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亚型
- IgG
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anti-Solute Carrier Family 26, Member 6 (SLC26A6) (AA 554-668) antibody
SLC26A6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 26, Member 6 (SLC26A6) (AA 666-738) antibodySLC26A6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Solute Carrier Family 26, Member 6 (SLC26A6) (Internal Region) antibodyVerified SLC26A6 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Solute Carrier Family 26, Member 6 (SLC26A6) (AA 1-758) antibodySLC26A6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 26, Member 6 (SLC26A6) (AA 1-758) antibodySLC26A6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Solute Carrier Family 26, Member 6 (SLC26A6) (AA 431-500) antibodySLC26A6 适用: Pig, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 26, Member 6 (SLC26A6) (Internal Region) antibodyVerified SLC26A6 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Solute Carrier Family 26, Member 6 (SLC26A6) (AA 613-662) antibodySLC26A6 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 26, Member 6 (SLC26A6) (AA 509-758) antibodySLC26A6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- SLC26A6 (Solute Carrier Family 26, Member 6 (SLC26A6))
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别名
- SLC26A6
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背景
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Synonyms: Solute carrier family 26 member 6, Anion exchange transporter, Pendrin-like protein 1, Pendrin-L1, SLC26A6
Background: Apical membrane anion-exchanger with wide epithelial distribution that plays a role as a component of the pH buffering system for maintaining acid-base homeostasis. Acts as a versatile DIDS-sensitive inorganic and organic anion transporter that mediates the uptake of monovalent anions like chloride, bicarbonate, formate and hydroxyl ion and divalent anions like sulfate and oxalate. Function in multiple exchange modes involving pairs of these anions, which include chloride-bicarbonate, chloride-oxalate, oxalate-formate, oxalate-sulfate and chloride-formate exchange. Apical membrane chloride-bicarbonate exchanger that mediates luminal chloride absorption and bicarbonate secretion by the small intestinal brush border membrane and contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption, possibly by providing a bicarbonate import pathway. Mediates also intestinal chloride absorption and oxalate secretion, thereby preventing hyperoxaluria and calcium oxalate urolithiasis. Transepithelial oxalate secretion, chloride-formate, chloride-oxalate and chloride-bicarbonate transport activities in the duodenum are inhibited by PKC activation in a calcium-independent manner. The apical membrane chloride-bicarbonate exchanger provides also a major route for fluid and bicarbonate secretion into the proximal tubules of the kidney as well as into the proximal part of the interlobular pancreatic ductal tree, where it mediates electrogenic chloride-bicarbonate exchange with a chloride-bicarbonate stoichiometry of 1:2, and hence will dilute and alkalinize protein-rich acinar secretion. Mediates also the transcellular sulfate absorption and oxalate secretion across the apical membrane in the duodenum and the formate ion efflux at the apical brush border of cells in the proximal tubules of kidney.
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基因ID
- 65010
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UniProt
- Q9BXS9
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途径
- Dicarboxylic Acid Transport
抗原
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