NOS1 抗体 (pSer1417)
Quick Overview for NOS1 抗体 (pSer1417) (ABIN4912434)
抗原
See all NOS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1417
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交叉反应
- 人, 大鼠, 非洲爪蟾
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预测反应
- Mouse,Zebrafish
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated Synthesised phosphopeptide derived from human nNOS around the phosphorylation site of Ser1417
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
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别名
- nNOS
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背景
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Synonyms: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP9
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
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基因ID
- 842
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UniProt
- P55211
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途径
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
抗原
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