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IL-10 抗体 (AA 51-100) (AbBy Fluor® 555)

This anti-IL-10 antibody is a 兔 多克隆 antibody detecting IL-10 in WB 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4910970
发货至: 中国

Quick Overview for IL-10 抗体 (AA 51-100) (AbBy Fluor® 555) (ABIN4910970)

抗原

See all IL-10 (IL10) 抗体
IL-10 (IL10) (Interleukin 10 (IL10))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IL-10 antibody is conjugated to AbBy Fluor® 555

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

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    AA 51-100

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IL-10

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    IL-10

    背景

    Synonyms: CSIF, TGIF, GVHDS, IL-10, IL10A, Interleukin-10, Cytokine synthesis inhibitory factor, IL10

    Background: Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. IL-10 Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

    基因ID

    3586

    UniProt

    P22301

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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