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GAPDH 抗体 (AA 1-335)

GAPDH 适用: 人, 小鼠, 大鼠, Pig WB, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4909877
发货至: 中国
  • 抗原 See all GAPDH 抗体
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    抗原表位
    • 33
    • 20
    • 13
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-335
    适用
    • 200
    • 137
    • 130
    • 69
    • 62
    • 53
    • 36
    • 27
    • 22
    • 20
    • 19
    • 19
    • 17
    • 16
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    • 11
    • 11
    • 9
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig
    宿主
    • 153
    • 89
    • 17
    • 9
    • 4
    克隆类型
    • 177
    • 93
    多克隆
    标记
    • 144
    • 33
    • 21
    • 16
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAPDH antibody is un-conjugated
    应用范围
    • 220
    • 88
    • 69
    • 64
    • 43
    • 36
    • 29
    • 22
    • 15
    • 15
    • 15
    • 13
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, Pig, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant full length human GAPDH
    亚型
    IgG
    Top Product
    Discover our top product GAPDH Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Jia, Wang, Wang, Wei, Li, Wu, Hong: "Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α." in: Journal of cellular and molecular medicine, Vol. 22, Issue 9, pp. 4507-4521, (2019) (PubMed).

    Yu, Zhao, Zhang, Xie, Nie, Shi: "Inhibition of microRNA-143-3p attenuates myocardial hypertrophy by inhibiting inflammatory response." in: Cell biology international, Vol. 42, Issue 11, pp. 1584-1593, (2018) (PubMed).

    Liang, Liu, Wang, Shen, Mei, Li, Liu: "Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways." in: Oncotarget, Vol. 8, Issue 17, pp. 28510-28525, (2018) (PubMed).

    Mu, Hui, Shao, Li, Du, Lu, Ye, Li, Li, Xiao, Qiu, Zhang, Fan, Ren, Tao, Xiang: "Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer." in: Oncotarget, Vol. 8, Issue 24, pp. 39443-39459, (2018) (PubMed).

    Yin, Jiang, Shi, Gui, Yu: "Expression and Clinical Significance of ILF2 in Gastric Cancer." in: Disease markers, Vol. 2017, pp. 4387081, (2018) (PubMed).

    Wang, Zhou, Xiong, Yu, Wu, Li, Yao, Wu, Hua: "Irreversible electroporation-mediated shRNA knockdown of the HPV18 E6 gene suppresses cervical cancer growth in vitro and in vivo." in: Oncology letters, Vol. 14, Issue 2, pp. 1943-1949, (2017) (PubMed).

    Lin, Geng, Zhao, Lin, Zhu, Tian: "MiR-21 Regulates TNF-α-Induced CD40 Expression via the SIRT1-NF-κB Pathway in Renal Inner Medullary Collecting Duct Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 1, pp. 124-136, (2017) (PubMed).

    Liu, Xiao: "Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia." in: BMC ophthalmology, Vol. 17, Issue 1, pp. 135, (2017) (PubMed).

    Zhou, Mu, Gong, Lu, Zhao, He, Qin: "Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expression." in: Redox biology, Vol. 11, pp. 390-402, (2017) (PubMed).

    Zong, Li, Zeng, Fang, Zhao: "The Effects of Interleukin-17 (IL-17)-Related Inflammatory Cytokines and A20 Regulatory Proteins on Astrocytes in Spinal Cord Cultured In Vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 3, pp. 1100-10, (2016) (PubMed).

    Yang, Dai, Tan, Zhang, Meng, Ye, Wang, Wei, He, Chen: "Lrig1 is a positive prognostic marker in hepatocellular carcinoma." in: OncoTargets and therapy, Vol. 9, pp. 7071-7079, (2016) (PubMed).

    Qiao, Chen, Dong, Ma, Zhao, Tang, Li: "Polydatin Attenuates H2O2-Induced Oxidative Stress via PKC Pathway." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5139458, (2016) (PubMed).

    Duan, Tu, Liu, Jiao: "Antidepressant effect of electroacupuncture regulates signal targeting in the brain and increases brain-derived neurotrophic factor levels." in: Neural regeneration research, Vol. 11, Issue 10, pp. 1595-1602, (2016) (PubMed).

    Guo, Zhao, Chen, Hu, Wang, Zhang, Sun: "BRAF-activated long non-coding RNA contributes to colorectal cancer migration by inducing epithelial-mesenchymal transition." in: Oncology letters, Vol. 8, Issue 2, pp. 869-875, (2014) (PubMed).

    Wang, Guo, Zhao, Chen, Wang, Hu, Sun: "BRAF-activated long non-coding RNA contributes to cell proliferation and activates autophagy in papillary thyroid carcinoma." in: Oncology letters, Vol. 8, Issue 5, pp. 1947-1952, (2014) (PubMed).

  • 抗原
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    别名
    GAPDH (GAPDH 产品)
    别名
    G3PD antibody, GAPD antibody, Gapd antibody, BEST:GH12586 antibody, CG12055 antibody, Dmel\\CG12055 antibody, GA3PDH antibody, GADPH antibody, GAP antibody, GAPDH antibody, GAPDH I antibody, GAPDH-1 antibody, GAPDH1 antibody, GAPDHI antibody, Gapdh antibody, Gapdh-1 antibody, Gapdh43E antibody, gadph antibody, gapdh antibody, gapdh-1 antibody, gh12586 antibody, cb609 antibody, gapd antibody, mg:bb02e05 antibody, wu:fb33a10 antibody, wu:ft80f05 antibody, KNC-NDS6 antibody, g3pd antibody, G3PDH antibody, glyceraldehyde-3-phosphate dehydrogenase antibody, Glyceraldehyde 3 phosphate dehydrogenase 1 antibody, glyceraldehyde-3-phosphate dehydrogenase S homeolog antibody, glyceraldehyde-3-phosphate dehydrogenase, type I antibody, olfactory receptor 8K3 antibody, GAPDH antibody, Gapdh antibody, Gapdh1 antibody, gapdh antibody, gapdh.S antibody, gapDH antibody, LOC100404960 antibody, LOC614985 antibody
    背景

    Synonyms: Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH, GAPD, CDABP0047, OK/SW-cl.12 bs-0755R

    Background: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

    基因ID
    2597
    UniProt
    P04406
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