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GAPDH 抗体 (AA 1-335)

Name: GAPDH 抗体 (AA 1-335)
SKU: ABIN4909877
Availability: OutOfStock

This anti-GAPDH antibody is a 兔多克隆 antibody detecting GAPDH in WB, ICC, IHC (p), IHC (fro), IF (cc) 和 IF (p). Suitable for 人, 小鼠, 大鼠和 Pig. This Primary Antibody has been cited in 19+ publications.

294T cell lysates probed with different dilutions of GAPDH Polyconal Antibody . (GAPDH 抗体 (AA 1-335))

1 image

(19 references)

产品编号 ABIN4909877

发货至: 中国

Quick Overview for GAPDH 抗体 (AA 1-335) (ABIN4909877)

抗原

See all GAPDH 抗体

GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

适用

人, 小鼠, 大鼠, Pig

宿主

兔

克隆类型

多克隆

标记

This GAPDH antibody is un-conjugated

应用范围

Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Discover our top product GAPDH Primary Antibody

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AA 1-335

交叉反应

人, 小鼠, Pig, 大鼠

纯化方法

Purified by Protein A.

免疫原

Recombinant full length human GAPDH

亚型

IgG
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) antibody
GAPDH 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (C-Term) antibody
Verified GAPDH 适用: 人, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (Internal Region) antibody
Verified GAPDH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 226-335) antibody
GAPDH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C2 unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 136-335) antibody
GAPDH 适用: 人, 小鼠, 大鼠, 小鸡, 猴, 斑马鱼 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) antibody
GAPDH 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A10A10 unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 62-91), (N-Term) antibody
GAPDH 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB16537 unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 2-148) antibody
GAPDH 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal D1 unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 154-324) antibody
GAPDH 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 2-148) antibody
GAPDH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Jia, Wang, Wang, Wei, Li, Wu, Hong: "Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α." in: Journal of cellular and molecular medicine, Vol. 22, Issue 9, pp. 4507-4521, (2019) (PubMed).

Yu, Zhao, Zhang, Xie, Nie, Shi: "Inhibition of microRNA-143-3p attenuates myocardial hypertrophy by inhibiting inflammatory response." in: Cell biology international, Vol. 42, Issue 11, pp. 1584-1593, (2018) (PubMed).

Liang, Liu, Wang, Shen, Mei, Li, Liu: "Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways." in: Oncotarget, Vol. 8, Issue 17, pp. 28510-28525, (2018) (PubMed).

Mu, Hui, Shao, Li, Du, Lu, Ye, Li, Li, Xiao, Qiu, Zhang, Fan, Ren, Tao, Xiang: "Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer." in: Oncotarget, Vol. 8, Issue 24, pp. 39443-39459, (2018) (PubMed).

Yin, Jiang, Shi, Gui, Yu: "Expression and Clinical Significance of ILF2 in Gastric Cancer." in: Disease markers, Vol. 2017, pp. 4387081, (2018) (PubMed).

Wang, Zhou, Xiong, Yu, Wu, Li, Yao, Wu, Hua: "Irreversible electroporation-mediated shRNA knockdown of the HPV18 E6 gene suppresses cervical cancer growth in vitro and in vivo." in: Oncology letters, Vol. 14, Issue 2, pp. 1943-1949, (2017) (PubMed).

Lin, Geng, Zhao, Lin, Zhu, Tian: "MiR-21 Regulates TNF-α-Induced CD40 Expression via the SIRT1-NF-κB Pathway in Renal Inner Medullary Collecting Duct Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 1, pp. 124-136, (2017) (PubMed).

Liu, Xiao: "Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia." in: BMC ophthalmology, Vol. 17, Issue 1, pp. 135, (2017) (PubMed).

Zhou, Mu, Gong, Lu, Zhao, He, Qin: "Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expression." in: Redox biology, Vol. 11, pp. 390-402, (2017) (PubMed).

Zong, Li, Zeng, Fang, Zhao: "The Effects of Interleukin-17 (IL-17)-Related Inflammatory Cytokines and A20 Regulatory Proteins on Astrocytes in Spinal Cord Cultured In Vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 3, pp. 1100-10, (2016) (PubMed).

Yang, Dai, Tan, Zhang, Meng, Ye, Wang, Wei, He, Chen: "Lrig1 is a positive prognostic marker in hepatocellular carcinoma." in: OncoTargets and therapy, Vol. 9, pp. 7071-7079, (2016) (PubMed).

Qiao, Chen, Dong, Ma, Zhao, Tang, Li: "Polydatin Attenuates H2O2-Induced Oxidative Stress via PKC Pathway." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5139458, (2016) (PubMed).

Duan, Tu, Liu, Jiao: "Antidepressant effect of electroacupuncture regulates signal targeting in the brain and increases brain-derived neurotrophic factor levels." in: Neural regeneration research, Vol. 11, Issue 10, pp. 1595-1602, (2016) (PubMed).

Guo, Zhao, Chen, Hu, Wang, Zhang, Sun: "BRAF-activated long non-coding RNA contributes to colorectal cancer migration by inducing epithelial-mesenchymal transition." in: Oncology letters, Vol. 8, Issue 2, pp. 869-875, (2014) (PubMed).

Wang, Guo, Zhao, Chen, Wang, Hu, Sun: "BRAF-activated long non-coding RNA contributes to cell proliferation and activates autophagy in papillary thyroid carcinoma." in: Oncology letters, Vol. 8, Issue 5, pp. 1947-1952, (2014) (PubMed).
抗原

GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

别名

GAPDH

背景

Synonyms: Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH, GAPD, CDABP0047, OK/SW-cl.12 bs-0755R
Background: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

基因ID

2597

UniProt

P04406