ESR2 抗体 (AA 201-300) (PE)
Quick Overview for ESR2 抗体 (AA 201-300) (PE) (ABIN4909264)
抗原
See all ESR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 201-300
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交叉反应
 - 人, 小鼠, 大鼠, 绵羊
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预测反应
 - Cow,Pig
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human ER-beta
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亚型
 - IgG
 
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应用备注
 - FCM 1:20-100
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
 - 12 months
 
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- ESR2 (Estrogen Receptor 2 (ESR2))
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别名
 - Estrogen receptor beta
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背景
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Synonyms: Erb, ESRB, ESTRB, NR3A2, ER-BETA, ESR-BETA, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2, ESR2
Background: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
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基因ID
 - 2100
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UniProt
 - Q92731
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途径
 - Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
 
抗原
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