EPH Receptor A5 抗体
Quick Overview for EPH Receptor A5 抗体 (ABIN4909184)
抗原
See all EPH Receptor A5 (EPHA5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- Purified His-tagged EPHA5 protein(Fragment) was used to produced this monoclonal antibody.
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亚型
- IgG1
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anti-EPH Receptor A5 (EPHA5) (AA 246-514) antibody
EPHA5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) (Internal Region) antibodyEPHA5 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 1-130) antibodyEPHA5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 620-774) antibodyEPHA5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8B10B1 unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 942-972), (C-Term) antibodyEPHA5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1658 unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 234-333) antibodyEPHA5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5C8 unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 234-333) antibodyEPHA5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 792-841) antibodyEPHA5 适用: 人, 小鼠, 大鼠, 小鸡, 猴, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) (AA 1001-1032), (C-Term) antibodyEPHA5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A5 (EPHA5) (Middle Region) antibodyEPHA5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- EPH Receptor A5 (EPHA5)
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别名
- EPHA5
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背景
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Synonyms: EK7, CEK7, EHK1, HEK7, EHK-1, TYRO4, Ephrin type-A receptor 5, Brain-specific kinase, EPH homology kinase 1, EPH-like kinase 7, EPHA5, BSK
Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).
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基因ID
- 2044
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UniProt
- P54756
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途径
- RTK signaling
抗原
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