FGFR2 抗体 (AA 809-821)
Quick Overview for FGFR2 抗体 (AA 809-821) (ABIN490845)
抗原
See all FGFR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 809-821
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特异性
- FGFR2, Cytoplasmic reacts specifically with FGFR2 using immunoblotting and immunoprecipitation (doublet at 115-125kD) using whole cell lysates of transfected 293T cells, a human, embryonic kidney cell line, expressing recombinant human FGFR2. No reaction with human FGFR1 and FGFR3 is detected. Species cross-reactivity: Human. Expected to cross-react with Mouse (92 % identity with immunogen) and Rat (92 % identity with immunogen) due to sequence homology.
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预测反应
- Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Horse (92%) Panda, Bovine, Dog (85%).
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纯化方法
- Immunoaffinity purified
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免疫原
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Synthetic peptide: KLPQYPHIGSVKT conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 809-821 of the cytoplasmic region of Human FGFR2. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Horse (92%), Panda, Bovine, Dog (85%).
Type of Immunogen: Synthetic peptide - KLH conjugated -
亚型
- IgG
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应用备注
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Approved: IHC, IHC-P, IP (1:2000), WB (1:2000)
Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Immunohistochemistry (trypsin or protease-digested, formalin-fixed, paraffin-embedded tissue):1:250, Immunoprecipitation: 1:2000, Western Blot:1:2000. Positive control: 293T, embryonic kidney cell line. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 1 % BSA, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
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别名
- FGF Receptor / FGFR2
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背景
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Name/Gene ID: FGFR2
Subfamily: FGF Receptor
Family: Protein Kinase
Synonyms: FGFR2, BEK, BBDS, Bacteria-expressed kinase, CD332 antigen, CFD1, Craniofacial dysostosis 1, CEK3, Fgf bek, FGF receptor, Hydroxyaryl-protein kinase, Jackson-Weiss syndrome, JWS, FGF Receptor 2, KSAM, KGFR, Soluble FGFR4 variant 4, BFR-1, TK14, TK25, CD332, ECT1, K-SAM -
基因ID
- 2263
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UniProt
- P21802
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
抗原
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