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Cortactin 抗体

CTTN 适用: 人 WB 宿主: 小鼠 Monoclonal 1T3 unconjugated
产品编号 ABIN4908251
发货至: 中国
  • 抗原 See all Cortactin (CTTN) 抗体
    Cortactin (CTTN)
    适用
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    宿主
    • 122
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    小鼠
    克隆类型
    • 114
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    单克隆
    标记
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    This Cortactin antibody is un-conjugated
    应用范围
    • 93
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    Western Blotting (WB)
    交叉反应
    纯化方法
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    免疫原
    Purified His-tagged Cortactin protein(Fragment) was used to produced this monoclonal antibody.
    克隆位点
    1T3
    亚型
    IgM
    Top Product
    Discover our top product CTTN Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Cortactin (CTTN)
    别名
    Cortactin (CTTN 产品)
    别名
    EMS1 antibody, 1110020L01Rik antibody, Ems1 antibody, Cttnb antibody, CG3637 antibody, Dmel\CG3637 antibody, cortactin antibody, cttn antibody, CTTN1 antibody, P85.25 antibody, Cttn antibody, ems1 antibody, CTTN antibody, cortactin antibody, CG3637 gene product from transcript CG3637-RD antibody, cortactin S homeolog antibody, cortactin L homeolog antibody, src substrate cortactin antibody, Src substrate cortactin antibody, CTTN antibody, Cttn antibody, Cortactin antibody, cttn.S antibody, cttn.L antibody, cttn antibody, CpipJ_CPIJ006351 antibody, Bm1_57220 antibody, LOC100533277 antibody
    背景

    Synonyms: EMS1, Src substrate cortactin, Amplaxin, Oncogene EMS1, CTTN

    Background: Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879). Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density (By similarity). Plays a role in the invasiveness of cancer cells, and the formation of metastases (PubMed:16636290). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed:20861316). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (PubMed:17959782). Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity). Required for stabilization of KCNH1 channels at the cell membrane (PubMed:23144454).

    基因ID
    2017
    UniProt
    Q14247
    途径
    MAPK Pathway
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