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Caspase 3 抗体 (AA 21-120) (HRP)

This anti-Caspase 3 antibody is a 兔 多克隆 antibody detecting Caspase 3 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN4907452
发货至: 中国

Quick Overview for Caspase 3 抗体 (AA 21-120) (HRP) (ABIN4907452)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

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人, 小鼠

宿主

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克隆类型

  • 224
  • 53
多克隆

标记

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This Caspase 3 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 21-120

    交叉反应

    人, 小鼠

    预测反应

    Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human caspase-3 p17 subunit

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Caspase 3 (CASP3)

    别名

    Caspase-3

    背景

    Synonyms: Caspase-3 subunit p17, APOPAIN, CASP3, Caspase 3 apoptosis related cysteine protease, Caspase3, CPP32, CPP32B, Cysteine protease CPP32, Human cysteine protease CPP32 isoform alpha mRNA complete cds, PARP cleavage protease, SCA 1, SCA1, SREBP cleavage activity 1, Yama, CASP3_HUMAN, Caspase-3, CASP-3, Apopain, Protein Yama, SREBP cleavage activity 1, SCA-1.

    Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

    基因ID

    836

    UniProt

    P42574

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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