ALDH2 抗体
Quick Overview for ALDH2 抗体 (ABIN4906009)
抗原
See all ALDH2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This ALDH2 Monoclonal antibody is generated from mouse immunized with ALDH2 recombinant protein.
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亚型
- IgG1
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
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别名
- ALDH2
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背景
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Synonyms: ALDM, ALDHI, ALDH-E2, Aldehyde dehydrogenase, mitochondrial, ALDH class 2, ALDH2
Background: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.
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基因ID
- 217
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UniProt
- P05091
抗原
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