CTNNB1 抗体
Quick Overview for CTNNB1 抗体 (ABIN4903403)
抗原
See all CTNNB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- β-Catenin is a key downstream effector in the Wnt signaling pathway (1). It is implicated in two major biological processes in vertebrates: early embryonic development (2) and tumorigenesis (3). CK1 phosphorylates β-catenin at Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3β (4-6). GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41 (7). Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines (8).
-
纯化方法
- Affinity purification
-
免疫原
- A synthetic peptide of human CTNNB1.
-
亚型
- IgG
-
-
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (N-Term) antibody
KO Validated CTNNB1 适用: 人 WB, IHC, IF, FACS, IHC (p), IP, ICC, IHC (fro), ChIP, CUT&RUN, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (N-Term) antibodyCTNNB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 2-781) antibodyCTNNB1 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 682-781) antibodyCTNNB1 适用: 人 WB, ELISA, IF, PLA, RNAi 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibodyCTNNB1 适用: 人 WB, IHC, IF, FACS, StM 宿主: 兔 Monoclonal CTNNB1-2030R unconjugated Recombinant Antibody
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibodyCTNNB1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 9C1 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibodyCTNNB1 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 6A3 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibodyCTNNB1 适用: 人, 大鼠, 犬, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 9H2 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibodyCTNNB1 适用: 人, 大鼠, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 12H7 unconjugated
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibodyCTNNB1 适用: 人, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1E10 unconjugated
-
-
应用备注
- WB 1:500-1:2000 , IHC 1:50-1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C.
-
-
- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
-
别名
- CTNNB1
-
基因ID
- 1499
-
UniProt
- P35222
-
途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
-
