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Caspase 3 抗体

This anti-Caspase 3 antibody is a 兔 单克隆 antibody detecting Caspase 3 in WB, IHC, ICC 和 IF. Suitable for 人.
产品编号 ABIN4903137
发货至: 中国

Quick Overview for Caspase 3 抗体 (ABIN4903137)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

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宿主

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克隆类型

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  • 52
单克隆

标记

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This Caspase 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 产品特性

    This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human CASP3.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 , IHC 1:50-1:200 , ICC 1:50-1:200 , IF 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20°C.
  • 抗原

    Caspase 3 (CASP3)

    别名

    Caspase-3

    基因ID

    836

    UniProt

    P42574

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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