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SIRT2 抗体

This anti-SIRT2 antibody is a 小鼠 单克隆 antibody detecting SIRT2 in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN4902262
发货至: 中国

Quick Overview for SIRT2 抗体 (ABIN4902262)

抗原

See all SIRT2 抗体
SIRT2 (Sirtuin 2 (SIRT2))

适用

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  • 1
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人, 大鼠, 小鼠

宿主

  • 76
  • 10
  • 1
小鼠

克隆类型

  • 66
  • 21
单克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This SIRT2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1D4-H11-H11
  • 原理

    Mouse monoclonal to SirT2.

    特异性

    This antibody detects endogenous levels of SirT2 and does not cross-react with related proteins.

    产品特性

    Mouse Monoclonal to SirT2.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Purified recombinant human SirT2 protein expressed in E.coli.

    亚型

    IgG2b
  • 应用备注

    WB 1:500-2000
    ELISA 1:10000-20000

    说明

    Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原

    SIRT2 (Sirtuin 2 (SIRT2))

    别名

    SirT2

    分子量

    43kDa

    基因ID

    22933

    UniProt

    Q8IXJ6
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