SIRT2 抗体
Quick Overview for SIRT2 抗体 (ABIN4902262)
抗原
See all SIRT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Mouse monoclonal to SirT2.
-
特异性
- This antibody detects endogenous levels of SirT2 and does not cross-react with related proteins.
-
产品特性
- Mouse Monoclonal to SirT2.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Purified recombinant human SirT2 protein expressed in E.coli.
-
亚型
- IgG2b
-
-
-
-
应用备注
-
WB 1:500-2000
ELISA 1:10000-20000 -
说明
-
Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
-
- SIRT2 (Sirtuin 2 (SIRT2))
-
别名
- SirT2
-
分子量
- 43kDa
-
基因ID
- 22933
-
UniProt
- Q8IXJ6
抗原
-