PPARD 抗体
Quick Overview for PPARD 抗体 (ABIN4902153)
抗原
See all PPARD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PPAR delta is a protein encoded by the PPARD gene which is approximately 49,9 kDa. PPAR delta is localised to the nucleus. It is involved in pyruvate metabolism and the citric acid cycle, gene expression, metabolism and nuclear receptor transcription pathway. This protein falls under the peroxisome proliferator-activated receptor family. It is a nuclear hormone receptor that binds peroxisome proliferators and controls the size and number of peroxisomes produced by cells. It may also function as an integrator of transcription repression and nuclear receptor signalling. PPAR delta is ubiquitously expressed with the highest levels in the placenta and skeletal muscle. Mutations in the PPARD gene may result in atherosclerosis. STJ97707 was developed from clone 2F9 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of PPAR delta.
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特异性
- PPAR Delta Mouse Monoclonal Antibody (2F9) detects endogenous levels of PPAR Delta
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产品特性
- Mouse Monoclonal to PPAR Delta.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
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免疫原
- Recombinant peptide derived from PPAR Delta
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亚型
- IgG1
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应用备注
- IHC 1:100-200
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说明
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Ubiquitous with maximal levels in placenta and skeletal muscle.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
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别名
- PPAR Delta
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基因ID
- 5467
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UniProt
- Q03181
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途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
抗原
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