Neurotrophin 3 抗体 (AA 180-230)
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- 抗原 See all Neurotrophin 3 (NTF3) 抗体
- Neurotrophin 3 (NTF3)
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抗原表位
- AA 180-230
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neurotrophin 3 antibody is un-conjugated
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应用范围
- ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- NT-3 is a protein encoded by the NTF3 gene which is approximately 29,4 kDa. NT-3 is secreted and is involved in apoptotic pathways in synovial fibroblasts, the GPCR pathway, ERK signalling, TGF-beta pathway and nanog in mammalian ESC pluripotency. This protein falls under the neurotrophin family. It controls survival and differentiation of mammalian neurons and is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo. NT-3 is expressed in the brain and peripheral tissues. Mutations in the NTF3 gene result in diabetic neuropathy and pediatric fibrosarcoma. STJ98718 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This polyclonal antibody binds to endogenous NT-3.
- 特异性
- The antibody detects endogenous NT-3.
- 产品特性
- Rabbit Polyclonal to NT-3.
- 纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- 免疫原
- Synthetic peptide from human NT-3 protein.
- 亚型
- IgG
- Top Product
- Discover our top product NTF3 Primary Antibody
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- 应用备注
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IHC-P 1:50-300
ELISA 1:5000-20000 - 说明
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Brain and peripheral tissues.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- Neurotrophin 3 (NTF3)
- 别名
- NT-3 (NTF3 产品)
- 别名
- HDNF antibody, NGF-2 antibody, NGF2 antibody, NT3 antibody, NT-3 antibody, wu:fl98d04 antibody, hdnf antibody, ngf-2 antibody, ngf2 antibody, nt-3 antibody, nt3 antibody, NTF3 antibody, AI316846 antibody, AI835689 antibody, Nt3 antibody, Ntf-3 antibody, neurotrophin 3 antibody, neurotrophin 3 S homeolog antibody, neurotrophin 3 L homeolog antibody, NTF3 antibody, ntf3 antibody, ntf3.S antibody, Ntf3 antibody, ntf3.L antibody
- 基因ID
- 4908
- UniProt
- P20783
- 途径
- RTK signaling, Neurotrophin Signaling Pathway
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