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MAP1LC3A 抗体

MAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 5G10 unconjugated
产品编号 ABIN4901877
发货至: 中国
  • 抗原 See all MAP1LC3A 抗体
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 161
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MAP1LC3A antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    LC3A is a protein encoded by the MAP1LC3A gene which is approximately 14,3 kD. LC3A is localised to the cytoplasm, cytoskeleton and autophagosome. It is involved in pathways such as the autophagy pathway, pink/parkin mediated mitophagy, ferroptosis, cellular senescence and pathways affecting insulin-like growth factor-Akt signalling. MAP1A and MAP1B fall under the LC3A protein. They are microtubule-associated proteins that mediate the physical interactions between microtubules and components of the cytoskeleton. LC3A is most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. Mutations in the LC3A gene may result in Nasu-Hakola disease , lacrimal gland adenocarcinoma and leber congenital amaurosis. STJ97755 was developed from clone 5G10. It was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous levels of LC3A.
    特异性
    LC3A Mouse Monoclonal Antibody (5G10) detects endogenous levels of LC3A
    产品特性
    Mouse Monoclonal to LC3A.
    纯化方法
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    免疫原
    synthetic peptide derived from LC3A
    克隆位点
    5G10
    亚型
    IgG1
    Top Product
    Discover our top product MAP1LC3A Primary Antibody
  • 应用备注
    WB 1:1000-2000
    IHC 1:100-200
    说明

    Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    别名
    LC3A (MAP1LC3A 产品)
    别名
    ATG8E antibody, LC3 antibody, LC3A antibody, MAP1ALC3 antibody, MAP1BLC3 antibody, 1010001H21Rik antibody, 4922501H04Rik antibody, LC3a antibody, MGC69006 antibody, zgc:77094 antibody, MGC89867 antibody, MAP1LC3A antibody, map1lc3a antibody, microtubule associated protein 1 light chain 3 alpha antibody, microtubule-associated protein 1 light chain 3 alpha antibody, microtubule associated protein 1 light chain 3 alpha S homeolog antibody, MAP1LC3A antibody, Map1lc3a antibody, map1lc3a.S antibody, map1lc3a antibody
    基因ID
    84557
    UniProt
    Q9H492
    途径
    Autophagy
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