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TFF1 抗体

This anti-TFF1 antibody is a 小鼠 单克隆 antibody detecting TFF1 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4901698
发货至: 中国

Quick Overview for TFF1 抗体 (ABIN4901698)

抗原

See all TFF1 抗体
TFF1 (Trefoil Factor 1 (TFF1))

适用

  • 82
  • 17
  • 14
  • 14
  • 9
人, 小鼠, 大鼠

宿主

  • 46
  • 45
小鼠

克隆类型

  • 50
  • 41
单克隆

标记

  • 56
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This TFF1 antibody is un-conjugated

应用范围

  • 54
  • 37
  • 35
  • 30
  • 16
  • 13
  • 9
  • 8
  • 6
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    HP-1α is a protein encoded by the CBX5 gene which is approximately 22,2 kDa. HP-1α is localised to the nucleus. It is involved in chromatin regulation and acetylation, E2F mediated regulation of DNA replication and aurora B signalling. It is a highly conserved non-histone protein that falls under the heterochromatin protein family. It has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins. It is also involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. HP-1α is expressed in the liver, nervous system, kidney, eye and intestine. Mutations in the CBX5 gene may result in Reynolds syndrome. STJ98895 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous HP-1α protein.

    特异性

    The antibody detects endogenous HP-1α protein.

    产品特性

    Mouse Monoclonal to HP-1α.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Recombinant peptide derived from HP-1alpha.
  • 应用备注

    WB 1:500-2000
    ELISA 1:10000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原

    TFF1 (Trefoil Factor 1 (TFF1))

    别名

    HP-1alpha

    分子量

    22kDa

    基因ID

    23468

    UniProt

    P45973

    途径

    EGFR Signaling Pathway
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