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DDIT3 抗体 (AA 10-90)

The 小鼠单克隆 anti-DDIT3 antibody is suitable to detect DDIT3 in samples from 人, 小鼠和大鼠. It has been validated for WB 和 IHC (p).

产品编号 ABIN4901264

发货至: 中国

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Quick Overview for DDIT3 抗体 (AA 10-90) (ABIN4901264)

抗原

See all DDIT3 抗体

DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

人, 小鼠, 大鼠

宿主

小鼠

克隆类型

单克隆

标记

This DDIT3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2B1

Discover our top product DDIT3 Primary Antibody

抗原表位
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16

11

11

10

7

7

7

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 10-90

原理

CHOP is a protein encoded by the DDIT3 gene which is approximately 19,1 kDa. CHOP is localised to the cytoplasm and nucleus. It is involved in the unfolded protein response, the MAPK signalling pathway and apoptosis modulation and signalling. This protein falls under the CCAAT/enhancer-binding protein family of transcription factors. It functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP and preventing their DNA binding activity. It is activated by endoplasmic reticulum stress and promotes apoptosis. CHOP is expressed in the muscle, nervous system, eye, liver and heart. Mutations in the DDIT3 gene may result in myxoid liposarcoma. STJ97774 was developed from clone 2B1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of DDIT3

特异性

CHOP Mouse Monoclonal Antibody (2B1) detects endogenous levels of DDIT3

产品特性

Mouse Monoclonal to CHOP.

纯化方法

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

免疫原

synthetic peptide derived from CHOP

亚型

IgG1
anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (C-Term) antibody
DDIT3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-169) antibody
DDIT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (N-Term) antibody
DDIT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (pSer30) antibody
DDIT3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (N-Term) antibody
DDIT3 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 120-149), (C-Term) antibody
DDIT3 适用: 人, 小鼠 WB, IF, FACS 宿主: 兔 Polyclonal RB13788 unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-169) antibody
DDIT3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (Ser301) antibody
DDIT3 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) antibody
KD Validated DDIT3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2955 unconjugated Recombinant Antibody

anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 1-90) antibody
DDIT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G3 unconjugated

应用备注

WB 1:1000-2000
IHC 1:100-200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze/thaw cycles.

储存条件

-20 °C

储存方法

Store at -20°C, and avoid repeat freeze-thaw cycles.
抗原

DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

别名

CHOP

基因ID

1649

UniProt

P35638

途径

Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis